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Framework for Addressing Uncertainty and Variability in Pesticide Risk Assessment
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CRD Guidance on how to use WEBFRAM for regulatory risk assessments

Click on the links below to download documents provided by the Chemicals Regulation Directorate for use with WEBFRAM.

  • Guidance Document on how to use Webfram for regulatory risk assessments
  • Appendix 1. Guidance on how to use Webfram website
  • Appendix 2. Instructions on how to use the bird and mammal model
  • Appendix 3. Instructions on how to use the aquatic model
  • Appendix 4. Webfram – Worked Examples
  • Appendix 5. Comparison of the current, deterministic risk assessment approach with probabilistic risk assessment
  • Appendix 6. Dealing with uncertainty – which endpoint should be used in regulatory risk assessments and decision-making, the median, lower or upper confidence interval?
  • Appendix 7. Distributions and assumptions used to model toxicity for birds and mammals
  • Appendix 8. Research report of the validation of the avian model
  • Appendix 9. Development of decision criteria for Webfram risk characterisations: threshold approach
  • Appendix 10. Risk assessment for birds and mammals
  • Appendix 11. Probabilistic calculation of aquatic exposure via spray drift
  • Appendix 13. How to derive a 'regulatory concentration'